What Does ceesdekker.net Mean?
What Does ceesdekker.net Mean?
Blog Article
‘The 2nd is nanopores, and that is our oldest line of investigate and that has now triggered DNA sequencers dependant on nanopores. We pull unique DNA strands via a nanopore and might then examine off the nucleotide sequence. Quite just lately, we even managed to read through out an individual protein for The very first time employing This method. But this line of study is not only about developing applications, and also about true biological questions.
It had been only during the 1990s nevertheless, when nanotechnology had State-of-the-art to a amount the place one molecules could possibly be manipulated, that the main experimental gadgets commenced to appear.
Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I
Our function was swiftly adopted up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
This yielded a breakthrough. Inside of only some months, we have been able to measure transportation by means of somebody single-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with an Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Our investigate ranges within the biophysics of DNA to artificial cells and further than. Be sure to take a look underneath for the spectrum of our latest initiatives.
‘In the beginning we looked at biological techniques using a physical check out and acted on the basis from the resources we understood. It took a couple of years just before we started out Functioning a lot more on the big biological issues. I then began to simply call it nanobiology, a expression that didn't exist at time.
Researching DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
You can help our writer matching process! When you notice any publications incorrectly attributed to this writer, please sign up and mark matches as appropriate or incorrect.
Incredibly cool, but that wasn’t genuinely where by my interest lay. I wished to pioneer And that i had the feeling that was no more possible, since the most attention-grabbing elementary insights experienced by now been uncovered. But my subject experienced formulated lots of exciting new tools to measure individual molecules. I decided which i wanted to utilize this to biology, to have a look at it from the Actual physical viewpoint.’
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial cell division
2006, first demonstration of molecular sorting inside a lab on the chip making use of biomotors; discovery of nanobubbles in stable-point out nanopores; and initially estimate of electrokinetic Power conversion in the nanofluidic channel
Visualization of unstained DNA nanostructures with Superior in-concentration transmission electron microscopy tactics
Reliable-condition nanopores have demonstrated being a shockingly multipurpose probe for one-molecule Investigation of DNA. I'll explain a number of our latest results – especially DNA knots – along with our initiatives to grow the capabilities of sound-state nanopores even additional, in the direction of one-protein detection, cees dekker graphene nanopores, plasmonic nanopores, and DNA origami nanopores.